检索范围:
排序: 展示方式:
《医学前沿(英文)》 2021年 第15卷 第3期 页码 416-437 doi: 10.1007/s11684-021-0852-7
关键词: surgical aortic valve replacement trans-catheter aortic valve implantation left ventricular hypertrophy and fibrosis myocardial force-velocity relationship His-Purkinje pacing renin-angiotensin system inhibitors coronary access impairment
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 351-355 doi: 10.1007/s11684-016-0465-8
This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries (RCA) were completely occluded during transcatheter aortic valve implantation (TAVI), leading to fatal hemodynamic disorder. Occlusions of RCA complicated by TAVI are rare. In addition, emergency cardiopulmonary bypass (CPB) played a critical role in rescuing our second patient. Both patients were admitted for “severe aortic stenosis,” and TAVIs were performed. The first patient’s blood pressure immediately dropped to 70/40 mmHg after the balloon expansion and did not increase much after the administration of aramine or fluid therapy. He did not receive emergency surgery and died after 1.5 h of resuscitation. The second patient’s blood pressure fluctuated greatly for several minutes after the valve implantation, ranging from 170/100 mmHg to 60/40 mmHg. Angiography revealed a total occlusion of RCA. Thoracic surgery with CPB was performed, and the patient survived.
关键词: aortic stenosis transcatheter aortic valve implantation right coronary occlusion cardiac group
The evolution of surgical and medical treatment of aortic root aneurysm
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 427-432 doi: 10.1007/s11684-014-0385-4
Since first report of aortic root replacement in 1968, the surgical risk and long term outcome of patients with aortic root aneurysm have been continuously improving. In the last 30 years, the surgical approach is also evolving towards more valve conservation with prophylactical intervention at an earlier clinical stage. Translational research has also led to emerging surgical innovation and new drug therapy. Their efficacies are currently under vigorous clinical trials and evaluations.
关键词: aortic root aneurysm aortic root replacement valve sparing root replacement personalised external aortic root support
Histopathological study of congenital aortic valve malformations in 32 children
HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying
《医学前沿(英文)》 2007年 第1卷 第1期 页码 74-78 doi: 10.1007/s11684-007-0015-5
Evaluation of the harmonic scalpel in open surgery for abdominal aortic aneurysm
null
《医学前沿(英文)》 2012年 第6卷 第1期 页码 85-88 doi: 10.1007/s11684-012-0174-x
The harmonic scalpel is a hemostatic device primarily designed for use in laparoscopic surgery. During the last few years, many surgeons have begun to use the harmonic scalpel in open surgery. Several papers have cited the benefits of the device compared with conventional knot-tying techniques; however, no evidence showing the advantages of using the harmonic scalpel in complicated abdominal aortic aneurysm (AAA) surgery has been presented. The aim of the present study is to determine the value of the harmonic scalpel in open operation for AAA. A total of 153 patients who underwent open surgery for AAA at the Department of Vascular Surgery of Guangdong General Hospital, China between January 2001 and December 2010, were retrospectively analyzed. Open surgery performed with the harmonic scalpel on 105 patients was compared with open operation using conventional knot-tying techniques on 48 patients. The operative time, intraoperative blood loss, total postoperative drainage fluid volumes, hospital stay, and postoperative complications between the two groups were compared. The harmonic scalpel group was associated with a shorter operation time (113.2±23.6 min vs. 232.1±39.2 min, P<0.01) and lower intraoperative blood loss (126.1±96.6 ml vs. 592.1±207.2 ml, P<0.01). Postoperative drainage fluid volumes were greater in the conventional surgery group than in the harmonic scalpel group (702.1±192.8 ml vs. 198.5±97.4 ml, P<0.01). The hospital stay was shorter for the harmonic scalpel group than for the conventional surgery group (10.7±3.3 d vs. 16.5±4.7 d, P<0.05). No differences between the postoperative complications or hospital mortality of the two groups were found. The harmonic scalpel is a safe and minimally invasive tool in open surgery for AAA and is associated with shorter operative time, shorter hospital stay, and lower intraoperative blood loss and postoperative drainage fluid volumes compared with conventional knot-tying techniques.
关键词: abdominal aortic aneurysm harmonic scalpel minimally invasive
Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,
《机械工程前沿(英文)》 2010年 第5卷 第3期 页码 328-335 doi: 10.1007/s11465-010-0026-9
关键词: reverse engineering aortic arch aneurysm surface model meshing finite element model
null
《医学前沿(英文)》 2017年 第11卷 第3期 页码 445-448 doi: 10.1007/s11684-017-0520-0
Establishing a long-term vascular access in patients exhibiting vascular access exhaustion is challenging. In this study, we reported a case of a direct catheterization in the superior vena cava of a hemodialysis patient with vascular access exhaustion and original dysfunctional catheter inserted via the left internal jugular vein. The direct catheterization was performed with cuffed tunnel catheter (CUFF) and guided by digital subtraction angiography (DSA) and multidetector computed tomography venography (MDCTV). The DSA and MDCTV results revealed an occlusion in the right innominate vein and thromboses in the left innominate, right internal jugular, subclavian, and femoral veins. The distal end of the superior vena cava was localized clearly by the original CUFF under DSA. Directed at the distal end of the superior vena cava, a 0.5-cm secondary puncture was introduced below the lateral head of the sternocleidomastoid muscle via the right neck area. This study is one of the few reports regarding direct catheterization of CUFF via the superior vena cava of a patient with vascular access exhaustion and CUFF dysfunction on the left internal jugular vein. We believe that our study can provide a new alternative for inserting central venous catheter for such patient.
关键词: superior vena cava intervention vascular access exhaustion catheterization tunneled cuffed hemodialysis catheter
《医学前沿(英文)》 2021年 第15卷 第3期 页码 438-447 doi: 10.1007/s11684-020-0826-1
关键词: sporadic thoracic aortic dissection exome sequencing gene COL3A1 case–control study extracellular matrix
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 419-426 doi: 10.1007/s11684-014-0383-6
Aneurysmal dilatation of the aortic sinuses of Valsalva has been most extensively documented in the setting of aortopathies, particularly Marfan syndrome. On the other hand, there is limited data in the literature about congenital sinus of Valsalva aneurysms outside this context. For the purpose of this review, we carried out a literature search on aneurysmal dilatation of the sinuses of Valsalva in Marfan syndrome, and compared this with congenital sinus of Valsalva aneurysms, also including data from a case series from our institution. In conclusion, there are differences in management of aortic dilatation in Marfan syndrome and congenital sinus of Valsalva aneurysms. Though less well-recognised, congenital aneurysms are often associated with significant morbidity and mortality and timely intervention is necessary.
关键词: sinus of Valsalva aneurysms Marfan syndrome aortic dissection
Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer
null
《医学前沿(英文)》 2014年 第8卷 第1期 页码 96-100 doi: 10.1007/s11684-014-0316-4
Lymph node metastasis has an important effect on prognosis of patients with ovarian cancer. Moreover, the impact of para-aortic lymph node (PAN) removal on patient prognosis is still unclear. In this study, 80 patients were divided into groups A and B. Group A consisted of 30 patients who underwent PAN+ pelvic lymph node (PLN) dissection, whereas group B consisted of 50 patients who only underwent PLN dissection. Analysis of the correlation between PAN clearance and prognosis in epithelial ovarian cancer was conducted. Nineteen cases of lymph node metastasis were found in group A, among whom seven cases were positive for PAN, three cases for PLN, and nine cases for both PAN and PLN. In group B, 13 cases were positive for lymph node metastasis. Our study suggested that the metastatic rate of lymph node is 40.0%. Lymph node metastasis was significantly correlated with FIGO stage, tumor differentiation, and histological type both in groups A and B (P<0.05). In groups A and B, the three-year survival rates were 77.9% and 69.0%, and the five-year survival rates were 46.7% and 39.2%, respectively. However, the difference was not statistically significant (P>0.05). The three-year survival rates of PLN metastasis in groups A and B were 68.5% and 41.4%, and the five-year survival rates were 49.7% and 26.4%, respectively. Furthermore, PLN-positive patients who cleared PAN had significantly higher survival rate (P=0.044). In group A, the three-year survival rates of positive and negative lymph nodes were 43.5% and 72.7%, and the five-year survival rates were 27.2% and 58.5%, respectively. The difference was statistically significant (P=0.048). Cox model analysis of single factor suggested that lymph node status affected the survival rate (P<0.01), which was the death risk factor. Consequently, in ovarian carcinoma cytoreductive surgery, resection of the para-aortic lymph node, which has an important function in clinical treatment and prognosis of patients with ovarian cancer, is necessary.
关键词: ovarian cancer para-aortic lymph node pelvic lymph node
钱七虎,何益寿
《中国工程科学》 2001年 第3卷 第5期 页码 32-34
长江越江交通通道工程对我国21世纪经济的稳定发展作用巨大,因此在越江交通通道工程方案的选择上不能唯桥是举,而要因地制宜和恰到好处地发挥桥梁和水下隧道各自的优势,总体上实行桥隧并举。
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 311-319 doi: 10.1007/s11684-016-0460-0
We evaluated the roles of calpain cleavage-related mutations of the integrin β3 cytoplasmic tail in integrin αIIbβ3 bidirectional signaling using a trans-dominant inhibition model. Chimeric Tac-β3 proteins (i.e., Tac-β3, Tac-β3D741, Tac-β3D747, Tac-β3D754, Tac-β3D759, and Tac-β3DNITY) consisting of the extracellular and transmembrane domains of human IL-2 receptor (Tac) and the human integrin β3 cytoplasmic domain were stably expressed in the 123 CHO cells harboring human glycoprotein Ib-IX and wild-type integrin αIIbβ3. The different cells were assayed for stable adhesion and spreading on immobilized fibrinogen, and for binding soluble fibrinogen representing outside-in and inside-out signaling events, respectively. The chimeric protein Tac-β3 inhibited, and Tac-β3DNITY partially attenuated stable adhesion and spreading. Tac-β3, Tac-β3D759, Tac-β3DNITY, and Tac-β3D754, but not Tac-β3D747 or Tac-β3D741, impaired the soluble fibrinogen binding. Results indicated that the bidirectional signaling was significantly inhibited by Tac-β3 and Tac-β3DNITY, albeit to a much lesser extent. Moreover, only inside-out signaling was impaired in the 123/Tac-β3D759 and 123/Tac-β3D754 cells in contrast to an intact bidirectional signaling in the 123/Tac-β3D747 and 123/Tac-β3D741 cells. In conclusion, the calpain cleavage of integrin β3 resulted in the regulatory effects on signaling by interrupting its interaction with cytoplasmic proteins rather than altering its conformation, and may thus regulate platelet function.
关键词: integrin β3 signal transduction trans-dominant inhibition model
Novel piezoelectric pump with “E”-shaped valve found from sub-experiments
Jianhui ZHANG, Jun HUANG, Xiaoqi HU, Qixiao XI,
《机械工程前沿(英文)》 2010年 第5卷 第2期 页码 212-218 doi: 10.1007/s11465-010-0009-x
关键词: piezoelectricity valve pump experiment “ E” -shaped valve
Nonlinear sealing force of a seawater balance valve used in an 11000-meter manned submersible
《机械工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0726-y
关键词: seawater balance valve sealing performance hybrid ANE model FEM minimum sealing force equation
Artificial bee colony optimization for economic dispatch with valve point effect
Yacine LABBI,Djilani Ben ATTOUS,Belkacem MAHDAD
《能源前沿(英文)》 2014年 第8卷 第4期 页码 449-458 doi: 10.1007/s11708-014-0316-8
关键词: artificial bee colony (ABC) algorithm economic dispatch (ED) valve-point effect optimization
标题 作者 时间 类型 操作
opportunities in improving left ventricular remodelling and clinical outcome following surgical and trans-catheteraortic valve replacement
期刊论文
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
null
期刊论文
Histopathological study of congenital aortic valve malformations in 32 children
HUANG Ping, WANG Hongwei, LI Yanping, CHENG Peixuan, LIU Qingjun, ZHANG Zhenlu, LIU Jianying
期刊论文
engineering in the construction of numerical simulation oriented patient-specific model of stented aortic
Xianlong MENG, Wenyu FU, Yun ZHANG, Aike QIAO,
期刊论文
direct cannulation of superior vena cava for a hemodialysis patient with an original dysfunctional catheter
null
期刊论文
Identification of variants associated with sporadic thoracic aortic dissection: a case--control study
期刊论文
Aneurysmal dilatation of the aortic sinuses of Valsalva — beyond Marfan syndrome: a single centre experience
null
期刊论文
Clinical significance of para-aortic lymph node dissection and prognosis in ovarian cancer
null
期刊论文
Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition
null
期刊论文
Novel piezoelectric pump with “E”-shaped valve found from sub-experiments
Jianhui ZHANG, Jun HUANG, Xiaoqi HU, Qixiao XI,
期刊论文